Clinical Significance
Anergy may be taken advantage of for therapeutic uses. The immune response to grafting of transplanted organs and tissues could be minimized without weakening the entire immune system— a side effect of immunosuppressive drugs like cyclosporine. Anergy may also be used to induce activated lymphocytes to become unresponsive with autoimmune diseases like diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Likewise, preventing anergy in response to a tumoral growth may help in anti-tumor responses.
Read more about this topic: Clonal Anergy
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“History is the interpretation of the significance that the past has for us.”
—Johan Huizinga (1872–1945)