Issue
Clarice and Lorenzo had 10 children:
- Lucrezia Maria Romola de' Medici (Florence, 4 August 1470 – 15 November 1553); married 10 September 1486 Jacopo Salviati and had 10 children, including Cardinal Giovanni Salviati, Cardinal Bernardo Salviati, Maria Salviati (mother of Cosimo I de' Medici, Grand Duke of Tuscany), and Francesca Salviati (mother of Pope Leo XI)
- Twins who died after birth (March 1471)
- Piero di Lorenzo de' Medici (Florence, 15 February 1472 – Garigliano River, 28 December 1503), ruler of Florence after his father's death, called "the Unfortunate"
- Maria Maddalena Romola de' Medici (Florence, 25 July 1473 – Rome, 2 December 1528), married 25 February 1487 Franceschetto Cybo (illegitimate son of Pope Innocent VIII) and had seven children
- Contessina Beatrice de' Medici (23 September 1474 - September 1474), died young
- Giovanni di Lorenzo de' Medici (Florence, 11 December 1475 – Rome, 1 December 1521), ascended to the Papacy as Pope Leo X on 9 March 1513
- Luisa de' Medici (Florence, 25 January 1477 – July 1488), also called Luigia, was betrothed to Giovanni de' Medici il Popolano but died young
- Contessina Antonia Romola de' Medici (Pistoia, 16 January 1478 – Rome, 29 June 1515); married 1494 Piero Ridolfi (1467 - 1525) and had five children, including Cardinal Niccolò Ridolfi
- Giuliano di Lorenzo de' Medici, Duke of Nemours (Florence, 12 March 1479 – Florence, 17 March 1516), created Duke of Nemours in 1515 by King Francis I of France
Read more about this topic: Clarice Orsini
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