CIF is an abbreviation that may stand for:
- California Interscholastic Federation, the governing body for high school sports in California
- Caltech Intermediate Form, geometry language for VLSI design, in which the primitives are coloured rectangles (similar to GDSII)
- Canada India Foundation, Canadian lobbying organization
- CFTR inhibitory factor (Cif), a virulence factor secreted by Pseudomonas aeruginosa
- China International Fund, Chinese company that funds large-scale national projects in developing countries
- Climate Investment Funds
- Coming into force, the process of legislation becoming effective
- Comment is Free (CiF), online comment section of The Guardian newspaper
- Common Intermediate Format, a video format common in video teleconferencing
- Community Infrastructure Fund (CIF), a method of UK government funding for transport infrastructure
- Cost, Insurance and Freight - a sales contract term indicating that price includes cost, insurance and freight
- Crystallographic Information File, a standard text file format for representing crystallographic information promulgated by the International Union of Crystallography (IUCr) - and the closely related Crystallographic Information Framework
- Cumulative incidence function, in epidemiology statistics, an expression of the probability of disease up to a given time
- Continuous Improvement Foundation, an Egyptian organization working in the field of Continuous Improvement.
- Cyprus Investment Firm