Structure
KCC2 is a member of the cation-chloride cotransporter (CCC) superfamily of proteins.
As with all CCC proteins, KCC2 is an integral membrane protein with 12 transmembrane domains and both N- and C-terminal cytoplasmic domains. The terminal cytoplasmic domains can be phosphorylated by kinases within the neuron for rapid regulation.
Read more about this topic: Chloride Potassium Symporter 5
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