Childers is a British surname and may mean:
- Alisa Childers (born 1975), American singer
- Ambyr Childers (born 1988), American actress
- Bob Childers (1946–2006), American country/folk singer-songwriter
- Buddy Childers (1926–2007), American jazz trumpeter
- Ernest Childers (1918–2005), American Army officer
- Erskine Barton Childers (1929–1996), Irish UN civil servant
- Erskine Hamilton Childers (1905–1974), 4th President of Ireland (1973–74)
- Hugh Childers (1827–1896), British and Australian Liberal statesman
- Jason Childers (born 1975), American Major League baseball player
- Mary Ann Childers, American television reporter
- Matt Childers (born 1978), American major League baseball player
- Molly Childers (1875–1964), American born Irish writer
- Milly Childers (1866–1922), English painter
- Naomi Childers (1892–1964), American silent film actress
- Nessa Childers, Irish Member of the European Parliament
- Rita Childers (1915–2010) First Lady of Ireland
- Robert Caesar Childers (1838–1876), British orientalist
- Robert Erskine Childers (1870–1922), author and Irish nationalist
- Robert L. Childers, Tennessee judge
- Rodney Childers (born 1976), American NASCAR crew chief
- Sam Childers (born 1962), American charity worker
- Travis Childers (born 1958), United States Representative, 1st District of Mississippi
- W. D. Childers, American politician, Member of the Florida Senate
Childers may also refer to:
- Childers, Queensland, Australia
- Childers Hill, Tennessee, an unincorporated community in Hardin County, Tennessee
- Childers reforms of the British army
- HMAS Childers, a patrol boat of the Australian Navy
- HMS Childers, the name of five ships of the Royal Navy
- Flying Childers, undefeated 18th century thoroughbred racehorse