Chell may refer to:
- Chell, a community on the northern edge of Stoke-on-Trent, Staffordshire.
- Chell (Star Trek), a Star Trek: Voyager character
- Chell (Portal), the protagonist of the 2007 video game Portal and its 2011 sequel Portal 2
- Chell, a chemical cell - used in the context of Bottom-up Synthetic Biology
People with the surname Chell:
- Carol Chell, British children's television presenter
- Joseph Chell, British footballer
- Walter Chell, Canadian cocktail inventor who invented the Caesar (cocktail)