Conclusion
In summary, ChIP-seq offers an alternative to ChIP-chip. STAT1 experimental ChIP-seq data have a high degree of similarity to results obtained by ChIP-chip for the same type of experiment, with >64% of peaks in shared genomic regions. Because the data are sequence reads, ChIP-seq offers a rapid analysis pipeline (as long as a high-quality genome sequence is available for read mapping, and the genome doesn't have repetitive content that confuses the mapping process) as well as the potential to detect mutations in binding-site sequences, which may directly support any observed changes in protein binding and gene regulation.
Read more about this topic: Ch IP-sequencing
Famous quotes containing the word conclusion:
“So this
Is man; so—what better conclusion is there—
The day will not follow night, and the heart
Of man has a little dignity, but less patience
Than a wolf’s,”
—Allen Tate (1899–1979)
“Girls who put out are tramps. Girls who don’t are ladies. This is, however, a rather archaic usage of the word. Should one of you boys happen upon a girl who doesn’t put out, do not jump to the conclusion that you have found a lady. What you have probably found is a lesbian.”
—Fran Lebowitz (b. 1951)
“The conclusion has never changed: the worst sort of people come here for the worst sort of reasons and put upon those of us who have conveniently forgotten where we came from and how we got here.”
—Anna Quindlen (b. 1952)