Cefn may refer to:
- Places
- Cefn (community), in Wrexham county borough, Wales
- Cefn Mawr, a large village in the community of Cefn
- Cefn Fault, a geological fault in Wales
- Sport
- Cefn Druids A.F.C., a football club based in Cefn Mawr, playing in the Cymru Alliance.
- F.C. Cefn, a football club based in Cefn Mawr, playing in the Welsh National League (Wrexham Area) Premier Division