CDM may stand for:
- Cadbury's Dairy Milk
- Celebrity Deathmatch, a claymation TV series
- Ceramic discharge metal-halide lamp, a lamp/light source
- Cervejas de Moçambique, a brewery in Mozambique affiliated with SABMiller
- Charged Device Model, used in electrostatic discharge testing
- Clean Development Mechanism, a Kyoto Protocol mechanism to assist developing countries reducing their greenhouse gas emissions
- Coalition for a Democratic Majority, a conservative group of Democrats in the 70s and 80s
- Code division multiplexing
- Cold dark matter, a scientific theory
- Collaborative decision making
- Consensus decision-making
- College of Dental Medicine, an acronym used by some US dental schools
- Combining Diacritical Marks, for keyboards
- Combustion detection module
- Common Diagnostic Model
- Compact Disc Maxi single
- Conceptual data model
- Consolidated Diamond Mines, the Namibian subsidiary of De Beers
- Construction (Design & Management) Regulations - used in the construction industry in the UK
- Corona del Mar, Newport Beach, California, A Beach and Community in Newport Beach, California
- DePaul University College of Computing and Digital Media
- Central Defending Midfielder
- Centre Defensive Midfielder a position in football popularised by the FIFA games, also known as a holding midfielder
- Cash Deposit Machine, in banks.