CD4+ T Cells And Antitumor Immunity
This discovery furthered the development of a previously hypothesized theory, the immunosurveillance theory. The immunosurveillance theory suggests that the immune system routinely patrols the cells of the body, and, upon recognition of a cell, or group of cells, that has become cancerous, it will attempt to destroy them, thus preventing the growth of some tumors. (Burnet, 1970) More recent evidence has suggested that immunosurveillance is only part of a larger role the immune system plays in fighting cancer. Remodeling of this theory has led to the progression of the immunoediting theory, in which there are 3 phases, Elimination, Equilibrium and Escape.
Read more about CD4+ T Cells And Antitumor Immunity: Tumour Antigens, CD8+ T Cells and Antitumour Immunity, CD4+ T Cells, A More Central Role, Th1 and Th2 CD4+T Cells, IFN-γ, MHC Class II and Immunotherapy, MHC Class I and Class II Pathways, Upregulation of MHC Class II
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