CBB can be abbreviation for:
- Celebrity Big Brother, a reality television franchise
- Connexion by Boeing, a mobile ISP formerly offered by The Boeing Company
- Central Bank of Barbados (CBB) See also: Barbados
- Circular barbell, a common design of body piercing jewelry
- Campeonato Brasileiro de Basquete
- Colby-Bates-Bowdoin, an athletic conference in Maine, United States
- The Canterbury-Bankstown Bulldogs, an Australian rugby league team
- An internet slang abbreviation for "can't be bothered" and "could be better"
- An abbreviation for Custom Built Backgammon
- Common Building Block, a set of standards for laptop components introduced by Intel, making it possible to take components from one CBB laptop into another possibly from a competing manufacturer
- Coomassie Brilliant Blue, a blue dye commonly used to stain proteins in SDS-PAGE/BN-PAGE gels
- Stock symbol on New York Stock Exchange for Cincinnati Bell
- The IATA code for Jórge Wilstermann International Airport, Cochabamba, Boliva
- Snake Term: Captive Bred and Born