Cayman may refer to
- Caiman, small crocodilians of Central and South America.
- Cayman Islands, an overseas territory of the United Kingdom;
- Grand Cayman, Cayman Brac, or Little Cayman, three islands that are part of the Cayman Islands;
- Porsche Cayman, a sports car produced by Porsche;
- Alligatoridae, of which caiman is a genus.
- AMD Radeon HD6900 GPU series, codenamed Cayman