Casagrande is a surname. Notable people with the surname include:
- Alan Casagrande de Moura (1987) Brazilian footballer
- Arthur Casagrande Austrian-American civil engineer
- Caroline Casagrande
- Dominique Casagrande
- Francesco Casagrande
- Marco Casagrande
- Walter Casagrande
- Adele Casagrande Founder of Fendi