Callosa may stand for:
- Callosa d'En Sarrià, a town located in the comarca of La Marina Baixa, in the province of Alicante, Spain.
- Callosa de Segura, a town located in the comarca of El Baix Segura, in the province of Alicante, Spain.
- Collinsia callosa, a species of flowering plant belonging to Collinsia genus.