Buxtehude ( ) is a town on the Este River in Northern Germany in the district of Stade and part of the Hamburg Metropolitan Region (Metropolregion Hamburg). Buxtehude is a steadily growing medium-sized town and the second largest in the district of Stade. It lies on the southern borders of the Altes Land within easy reach of the city-state of Hamburg. West of it are the towns of Horneburg and Stade and to the south there are incorporated villages offering mostly upscale housing, e.g. Ottensen and Apensen.
Buxtehude is home to several large businesses and numerous smaller ones and retailers.