The biosphere is the global sum of all ecosystems. It can also be called the zone of life on Earth, a closed (apart from solar and cosmic radiation), and self-regulating system. From the broadest biophysiological point of view, the biosphere is the global ecological system integrating all living beings and their relationships, including their interaction with the elements of the lithosphere, hydrosphere, and atmosphere. The biosphere is postulated to have evolved, beginning through a process of biogenesis or biopoesis, at least some 3.5 billion years ago.

In a broader sense; biospheres are any closed, self-regulating systems containing ecosystems; including artificial ones such as Biosphere 2 and BIOS-3; and, potentially, ones on other planets or moons.

Read more about Biosphere:  Origin and Use of The Term, Extent of Earth's Biosphere, Specific Biospheres