History
Before the 1950s, opioids, and amphetamines, were commonly used as antidepressants. Their use was later restricted due to their addictive nature and side-effects. Extracts from the herb St John's wort had been used as a "nerve tonic" to alleviate depression.
Read more about this topic: Bicyclic Antidepressants
Famous quotes containing the word history:
“The history of this country was made largely by people who wanted to be left alone. Those who could not thrive when left to themselves never felt at ease in America.”
—Eric Hoffer (1902–1983)