BCL6

BCL6

Identifiers Symbols BCL6; BCL5; BCL6A; LAZ3; ZBTB27; ZNF51 External IDs OMIM: 109565 MGI: 107187 HomoloGene: 7640 GeneCards: BCL6 Gene

Gene Ontology
Molecular function	• chromatin binding • sequence-specific DNA binding transcription factor activity • protein binding • zinc ion binding • chromatin DNA binding • sequence-specific DNA binding • metal ion binding
Cellular component	• nucleus • replication fork • nucleolus
Biological process	• protein import into nucleus, translocation • negative regulation of transcription from RNA polymerase II promoter • cell morphogenesis • negative regulation of cell-matrix adhesion • germinal center formation • regulation of germinal center formation • negative regulation of type 2 immune response • negative regulation of B cell apoptotic process • transcription, DNA-dependent • response to DNA damage stimulus • Rho protein signal transduction • spermatogenesis • negative regulation of cell proliferation • actin cytoskeleton organization • B cell differentiation • negative regulation of cell growth • positive regulation of B cell proliferation • regulation of Rho GTPase activity • negative regulation of mast cell cytokine production • negative regulation of Rho protein signal transduction • type 2 immune response • positive regulation of apoptotic process • regulation of memory T cell differentiation • negative regulation of T-helper 2 cell differentiation • negative regulation of S phase of mitotic cell cycle • negative regulation of transcription, DNA-dependent • negative regulation of isotype switching to IgE isotypes • erythrocyte development • regulation of inflammatory response • regulation of immune response • positive regulation of cellular component movement
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 604 12053 Ensembl ENSG00000113916 ENSMUSG00000022508 UniProt P41182 P41183 RefSeq (mRNA) NM_001130845 NM_009744 RefSeq (protein) NP_001124317 NP_033874 Location (UCSC) Chr 3:
187.44 – 187.46 Mb Chr 16:
23.97 – 23.99 Mb PubMed search

B-cell lymphoma 6 protein is a protein that in humans is encoded by the BCL6 gene.