Bcl6

BCL6

Identifiers Symbols BCL6; BCL5; BCL6A; LAZ3; ZBTB27; ZNF51 External IDs OMIM: 109565 MGI: 107187 HomoloGene: 7640 GeneCards: BCL6 Gene

Gene Ontology
Molecular function • chromatin binding
• sequence-specific DNA binding transcription factor activity
• protein binding
• zinc ion binding
• chromatin DNA binding
• sequence-specific DNA binding
• metal ion binding
Cellular component • nucleus
• replication fork
• nucleolus
Biological process • protein import into nucleus, translocation
• negative regulation of transcription from RNA polymerase II promoter
• cell morphogenesis
• negative regulation of cell-matrix adhesion
• germinal center formation
• regulation of germinal center formation
• negative regulation of type 2 immune response
• negative regulation of B cell apoptotic process
• transcription, DNA-dependent
• response to DNA damage stimulus
• Rho protein signal transduction
• spermatogenesis
• negative regulation of cell proliferation
• actin cytoskeleton organization
• B cell differentiation
• negative regulation of cell growth
• positive regulation of B cell proliferation
• regulation of Rho GTPase activity
• negative regulation of mast cell cytokine production
• negative regulation of Rho protein signal transduction
• type 2 immune response
• positive regulation of apoptotic process
• regulation of memory T cell differentiation
• negative regulation of T-helper 2 cell differentiation
• negative regulation of S phase of mitotic cell cycle
• negative regulation of transcription, DNA-dependent
• negative regulation of isotype switching to IgE isotypes
• erythrocyte development
• regulation of inflammatory response
• regulation of immune response
• positive regulation of cellular component movement
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 604 12053 Ensembl ENSG00000113916 ENSMUSG00000022508 UniProt P41182 P41183 RefSeq (mRNA) NM_001130845 NM_009744 RefSeq (protein) NP_001124317 NP_033874 Location (UCSC) Chr 3:
187.44 – 187.46 Mb Chr 16:
23.97 – 23.99 Mb PubMed search

B-cell lymphoma 6 protein is a protein that in humans is encoded by the BCL6 gene.

Read more about Bcl6.