Axon Terminal - Mapping Activity

Mapping Activity

Structure of a typical neuron
Neuron
Dendrite Soma Axon Nucleus Node of
Ranvier Axon terminal Schwann cell Myelin sheath

Dr. Wade Regehr, professor of Neurobiology developed a method to physiologically see the synaptic activity that occurs in the brain. A dye alters the fluorenscence properties when attached to calcium. Using fluorescence-microscopy techniques calcium levels are detected, and therefore the influx of calcium in the presynaptic neuron. Regehr's laboratory specializes in pre-synaptic calcium dynamics which occurs at the axon terminals. Regehr studies the implication of calcium Ca2+ as it affects synaptic strength. By studying the physiological process and mechanisms, a further understanding is made of neurological disorders such as epilepsy, schizophrenia and major depressive disorder, as well as memory and learning.

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    A worm is as good a traveler as a grasshopper or a cricket, and a much wiser settler. With all their activity these do not hop away from drought nor forward to summer. We do not avoid evil by fleeing before it, but by rising above or diving below its plane; as the worm escapes drought and frost by boring a few inches deeper.
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