AXIN1
| Gene Ontology | |
|---|---|
| Molecular function | • p53 binding • signal transducer activity • GTPase activator activity • protein binding • beta-catenin binding • protein C-terminus binding • enzyme binding • protein kinase binding • ubiquitin protein ligase binding • protein complex scaffold • identical protein binding • protein homodimerization activity • protein self-association • SMAD binding • armadillo repeat domain binding • I-SMAD binding • R-SMAD binding |
| Cellular component | • nucleus • cytoplasm • cytosol • cytoplasmic microtubule • plasma membrane • cell cortex • postsynaptic density • cytoplasmic membrane-bounded vesicle • lateral plasma membrane • beta-catenin destruction complex • cytoplasmic vesicle • perinuclear region of cytoplasm • cell periphery |
| Biological process | • protein polyubiquitination • in utero embryonic development • optic placode formation • positive regulation of protein phosphorylation • nucleocytoplasmic transport • apoptotic process • activation of JUN kinase activity • determination of left/right symmetry • sensory perception of sound • cell death • dorsal/ventral axis specification • positive regulation of peptidyl-threonine phosphorylation • forebrain anterior/posterior pattern specification • Wnt receptor signaling pathway involved in forebrain neuron fate commitment • protein catabolic process • negative regulation of Wnt receptor signaling pathway • positive regulation of transforming growth factor beta receptor signaling pathway • olfactory placode formation • cytoplasmic microtubule organization • positive regulation of protein ubiquitination • activation of protein kinase activity • positive regulation of proteasomal ubiquitin-dependent protein catabolic process • positive regulation of peptidyl-serine phosphorylation • negative regulation of transcription elongation from RNA polymerase II promoter • regulation of catenin import into nucleus • termination of G-protein coupled receptor signaling pathway • positive regulation of GTPase activity • cellular protein complex assembly • negative regulation of fat cell differentiation • positive regulation of protein catabolic process • positive regulation of transcription, DNA-dependent • positive regulation of JNK cascade • embryonic eye morphogenesis • axial mesoderm formation • negative regulation of protein metabolic process • protein homooligomerization • positive regulation of ubiquitin-protein ligase activity • muscle cell development • canonical Wnt receptor signaling pathway • embryonic skeletal joint morphogenesis • canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation • cellular response to organic cyclic compound • genetic imprinting • negative regulation of canonical Wnt receptor signaling pathway • Wnt receptor signaling pathway involved in somitogenesis • positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
| Sources: Amigo / QuickGO | |
0.34 – 0.4 Mb
26.14 – 26.2 Mb
Axin-1 is a protein that in humans is encoded by the AXIN1 gene.
Read more about Axin1.