Atopy - Treatments

Treatments

Corticosteroids: For years, there was no treatment for atopic eczema. Atopy was believed to be allergic in origin due to the patients’ extremely high serum IgE levels, but standard therapies at the time did not help. Oral prednisone was sometimes prescribed for severe cases. Wet wraps (covering the patients with gauze like a mummy) were sometimes used in hospitals to control itching. However, a true medical miracle occurred in the 1950s with the discovery that corticosteroids could be used topically in creams or ointments for atopic eczema and other conditions. Thus, the use of topical steroids avoided many of the undesirable side-effects of systemic administration of corticosteroids. Topical steroids control the itching and the rash that accompany atopic eczema. Side-effects of topical steroid use are plentiful, and the patient is advised to use topical steroids in moderation and only as needed.

Immune modulators: Pimecrolimus and tacrolimus creams and ointments became available in the 1980s, and are sometimes prescribed for atopic eczema. They act by interfering with T cells, but have been linked to the development of cancer.

Avoiding dry skin: Dry skin is a common feature of patients with atopic eczema (see also eczema for information), and can exacerbate atopic eczema.

Avoiding allergens and irritants: See eczema for information.

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