ASPH
| Gene Ontology | |
|---|---|
| Molecular function | • peptide-aspartate beta-dioxygenase activity • structural molecule activity • calcium ion binding • protein binding • structural constituent of muscle • electron carrier activity • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| Cellular component | • endoplasmic reticulum • endoplasmic reticulum membrane • plasma membrane • junctional sarcoplasmic reticulum membrane • integral to endoplasmic reticulum membrane • cortical endoplasmic reticulum |
| Biological process | • muscle contraction • pattern specification process • biological_process • negative regulation of cell proliferation • positive regulation of calcium ion transport into cytosol • regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum • regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity • activation of store-operated calcium channel activity • response to ATP • limb morphogenesis • peptidyl-aspartic acid hydroxylation • positive regulation of transcription, DNA-dependent • palate development • negative regulation of ryanodine-sensitive calcium-release channel activity • positive regulation of ryanodine-sensitive calcium-release channel activity • face morphogenesis • calcium ion transmembrane transport • cellular response to calcium ion • positive regulation of intracellular protein transport |
| Sources: Amigo / QuickGO | |
62.41 – 62.63 Mb
9.45 – 9.67 Mb
Aspartyl/asparaginyl beta-hydroxylase (HAAH) is an enzyme that in humans is encoded by the ASPH gene.
Read more about ASPH: Function, Clinical Significance