Aromatase Inhibitor - Types of AIs

Types of AIs

There are 2 types of aromatase inhibitors (AIs) approved to treat breast cancer:

  • Irreversible steroidal inhibitors, such as exemestane (Aromasin), forms a permanent and deactivating bond with the aromatase enzyme.
  • Non-steroidal inhibitors, such as anastrozole (Arimidex), inhibit the synthesis of estrogen via reversible competition for the aromatase enzyme.

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