Alpha Motor Neuron

Alpha Motor Neuron

Alpha motor neurons (α-MNs) are large lower motor neurons of the brainstem and spinal cord. They innervate extrafusal muscle fibers of skeletal muscle and are directly responsible for initiating their contraction. Alpha motor neurons are distinct from gamma motor neurons, which innervate intrafusal muscle fibers of muscle spindles.

While their cell bodies are found in the central nervous system (CNS), alpha motor neurons are also considered part of the somatic nervous system—a branch of the peripheral nervous system (PNS)—because their axons extend into the periphery to innervate skeletal muscles.

An alpha motor neuron and the muscle fibers it innervates is a motor unit. A motor neuron pool contains the cell bodies of all the alpha motor neurons involved in contracting a single muscle.

Read more about Alpha Motor Neuron:  Location, Connectivity, Signaling, Role in Disease, Development

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