Alpha-Latrotoxin

Alpha-Latrotoxin

α-Latrotoxin (α-LTX) can naturally be found in widow spiders of the genus Latrodectus. The most famous of those spiders are the black widows, Latrodectus mactans. The venom of widow spiders (Latrodectus) contains several protein toxins, called latrotoxins, which selectively target against either vertebrates, insects or crustaceans. One of these toxins is α-latrotoxin and targets selectively against vertebrates; it is ineffective in insects and crustaceans. α-LTX has a high affinity for receptors that are specific for neuronal and endocrine cells of vertebrates.

Read more about Alpha-Latrotoxin:  Incidents, Biosynthesis, Toxicokinetics, Toxicodynamics, Structure Activity Relationship (SAR), Toxicity, Clinical Symptoms, Treatment, Scientific Contribution