Alpha-fetoprotein

Identifiers Symbols AFP; FETA; HPAFP External IDs OMIM: 104150 MGI: 87951 HomoloGene: 36278 GeneCards: AFP Gene

Gene Ontology
Molecular function	• metal ion binding
Cellular component	• extracellular space • cytoplasm
Biological process	• ovulation from ovarian follicle • liver development • transport • response to organic substance • pancreas development • organ regeneration • progesterone metabolic process • SMAD protein signal transduction
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 174 11576 Ensembl ENSG00000081051 ENSMUSG00000054932 UniProt P02771 P02772 RefSeq (mRNA) NM_001134.1 NM_007423.4 RefSeq (protein) NP_001125.1 NP_031449.3 Location (UCSC) Chr 4:
74.3 – 74.32 Mb Chr 5:
90.49 – 90.51 Mb PubMed search

Alpha-Fetal Protein (AFP, α-fetoprotein; also sometimes called alpha-1-fetoprotein or alpha-fetoglobulin) is a protein that in humans is encoded by the AFP gene. The AFP gene is located on the q arm of chromosome 4 (4q25).