Agyeman is a surname. Notable people with the surname include:
- Agyeman Prempeh Opoku (born 1989), Ghanaian professional footballer
- Albert Agyeman (born 1977), retired Ghanaian sprinter, specialized in the 200 metres
- Dickson Agyeman (born 1985), Belgian football midfielder
- Edward Agyeman-Duah (born 1973), retired Ghanaian football defender
- Emmanuel Badu Agyeman (born 1990), Ghanaian international footballer
- Fredua Agyeman (1797–1867), the Asantehene (King of the Ashanti) from 1834 until 1867
- Freema Agyeman (born 1979), British actress
- Hackman Owusu-Agyeman (born 1941), member of Parliament for New Juabeng North constituency in Ghana
- Jot Agyeman (born 1967), Ghanaian actor, Media Practitioner and television anchor
- Nana Konadu Agyeman Rawlings (born 1948), the First Lady of Ghana
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