AFPep (Alpha Fetoprotein Peptide) is an orally active cyclic peptide with molecular weight of 969 Daltons and is derived from the anti-oncogenic active site (residues 472-479) of alpha fetoprotein (AFP). Using the standard amino acid abbreviations, AFPep has the sequence cyclo-(EKTOVNOGN), where O is hydroxyproline. This peptide has been shown in experimental animal models to be efficacious in the prevention and treatment of ER+ breast cancer.
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