Work
As late as the 1840s, and despite Friedrich Wöhler's synthesis of urea in 1828, some chemists still believed in the doctrine of vitalism, according to which a special life-force was necessary to create organic compounds. Kolbe developed the idea that organic compounds could be derived from inorganic ones, directly or indirectly, by substitution processes. He validated his theory by converting carbon disulfide, in several steps, to acetic acid (1843–45). Introducing a modified idea of structural radicals, he contributed to the establishment of structural theory. One of the more dramatic successes of his theory was his prediction of the existence of secondary and tertiary alcohols, a conjecture that was soon confirmed by the synthesis of these substances.
He worked on the electrolysis of the salts of fatty and other acids (Kolbe electrolysis) and prepared salicylic acid, a building block of aspirin in a process called Kolbe synthesis or Kolbe-Schmitt reaction. A certain method for the synthesis of nitriles is called the Kolbe nitrile synthesis.
Hermann Kolbe was the first person to use the word synthesis in the present day meaning.
With Edward Frankland he found that nitriles can be hydrolyzed to the corresponding acids.
Read more about this topic: Adolph Wilhelm Hermann Kolbe
Famous quotes containing the word work:
“Children, then, acquire social skills not so much from adults as from their interactions with one another. They are likely to discover through trial and error which strategies work and which do not, and later to reflect consciously on what they have learned.”
—Zick Rubin (20th century)
“It is easy to see that what is best written or done by genius in the world, was no man’s work but came by wide social labor, when a thousand wrought like one, sharing the same impulse.”
—Ralph Waldo Emerson (1803–1882)
“Many women who used to be full-time mothers are discovering that outside work gives them friends, challenges, variety, money, independence; it makes them feel better about themselves, and therefore lets them be better parents.”
—Wendy Coppedge Sanford. Ourselves and Our Children, by Boston Women’s Health Book Collective, introduction (1978)