In biology the active site is part of an enzyme where substrates bind and undergo a chemical reaction. The majority of enzymes are proteins but RNA enzymes called ribozymes also exist. The active site of an enzyme is usually found in a cleft or pocket that is lined by amino acid residues (or nucleotides in ribozymes) that participate in recognition of the substrate. Residues that directly participate in the catalytic reaction mechanism are called active site residues.
Read more about Active Site: Binding Mechanism, Chemistry
Famous quotes containing the words active and/or site:
“There is not enough exercise in this way of life. I try to make up by active gymnastics before I dress when I get up, by walking rapidly in the lower hall and the greenhouse after each meal for perhaps five to ten minutes, and a good hand rubbing before going to bed. I eat moderately; drink one cup of coffee at breakfast and one cup of tea at lunch and no other stimulant. My health is now, and usually, excellent.”
—Rutherford Birchard Hayes (1822–1893)
“I am not aware that any man has ever built on the spot which I occupy. Deliver me from a city built on the site of a more ancient city, whose materials are ruins, whose gardens cemeteries. The soil is blanched and accursed there, and before that becomes necessary the earth itself will be destroyed.”
—Henry David Thoreau (1817–1862)