Round 2
- (week ending 19th February)
| Tie no | Home team | Score | Away team |
|---|---|---|---|
| 1 | Leigh Miners | 38-26 | Oulton Raiders |
| 2 | Warrington Wizards | 20-22 | Bradford Dudley Hill |
| 3 | East Hull | 10-8 | Wigan St Patricks |
| 4 | Hunslet Warriors | 30-18 | Siddal |
| 5 | East Leeds | 22-46 | Widnes St Maries |
| 6 | York Acorn | 35-16 | Seaton Rangers |
| 7 | Walney Central | 0-28 | Saddleworth Rangers |
| 8 | Ovenden | 38-24 | Blackbrook |
| 9 | Skirlaugh | 25-12 | Wath Brow Hornets |
| 10 | Bramley Buffaloes | 22-28 | Shaw Cross Sharks |
| 11 | Barrow Island | 18-28 | Kells |
| 12 | The Army | 14-20 | West Bowling |
| 13 | Leigh East | 14-32 | Thornhill Trojans |
Read more about this topic: 2006 Challenge Cup