Zek may refer to:
- Zek (inmate), a Russian slang term for a prison or forced labor camp inmate
- Grand Nagus Zek, a Star Trek character.
- Zek, an EverQuest special game server
- Achmet Zek, a character from Tarzan the Tiger movie serial
- "Zentralstelle zur Erforschung der Kriegschuldfrage", Centre for the Study of the Causes of the War
- "Zentralstelle für Kreditinformation", a Swiss credit information center.