Ube2d3

UBE2D3

Identifiers Symbols UBE2D3; E2(17)KB3; UBC4/5; UBCH5C External IDs OMIM: 602963 MGI: 1913355 HomoloGene: 123914 GeneCards: UBE2D3 Gene EC number 6.3.2.19

Gene Ontology
Molecular function	• ubiquitin-protein ligase activity • protein binding • ATP binding
Cellular component	• nucleoplasm • cytosol • plasma membrane • endosome membrane
Biological process	• negative regulation of transcription from RNA polymerase II promoter • protein polyubiquitination • toll-like receptor signaling pathway • MyD88-independent toll-like receptor signaling pathway • DNA repair • transcription, DNA-dependent • transcription initiation from RNA polymerase II promoter • cellular protein modification process • ubiquitin-dependent protein catabolic process • protein monoubiquitination • apoptotic process • transforming growth factor beta receptor signaling pathway • gene expression • protein ubiquitination • BMP signaling pathway • negative regulation of type I interferon production • cellular response to stress • toll-like receptor 3 signaling pathway • toll-like receptor 4 signaling pathway • TRIF-dependent toll-like receptor signaling pathway • proteasomal ubiquitin-dependent protein catabolic process • innate immune response • regulation of transcription from RNA polymerase II promoter in response to hypoxia • protein K48-linked ubiquitination • protein K11-linked ubiquitination • cellular response to hypoxia
Sources: Amigo / QuickGO

Orthologs Species Human Mouse Entrez 7323 66105 Ensembl ENSG00000109332 ENSMUSG00000078578 UniProt P61077 P61079 RefSeq (mRNA) NM_003340 NM_025356 RefSeq (protein) NP_003331 NP_079632 Location (UCSC) Chr 4:
103.72 – 103.79 Mb Chr 3:
135.44 – 135.47 Mb PubMed search

Ubiquitin-conjugating enzyme E2 D3 is a protein that in humans is encoded by the UBE2D3 gene.