Tuckahoe may refer to Tuckahoe-Cohee, an early American cultural sub-group.
It may also refer to:
- Buildings
- Tuckahoe (Jensen Beach, Florida), or the Leach Mansion, in Jensen Beach, Florida
- Tuckahoe Plantation, boyhood home of Thomas Jefferson, in Virginia
- Bodies of water
- Tuckahoe Bay, in South Carolina
- Tuckahoe Creek, in Maryland
- Tuckahoe River (New Jersey)
- Places
- Tuckahoe, New Jersey, an unincorporated community in Upper Township
- Tuckahoe, Suffolk County, New York, a hamlet in Suffolk County
- Tuckahoe, Virginia, a census-designated place in Henrico County
- Tuckahoe (village), New York, a village in Westchester County
- Tuckahoe marble quarries
- Tuckahoe (Metro-North station), railroad station
- Tuckahoe State Park, in Maryland
- Other uses
- Wolfiporia extensa, also called Poria cocos, Tuckahoe, or Indian Bread; the sclerotium of a fungus used as food by Native Americans and by the Chinese as a medicinal
- Camp Tuckahoe, a Boy Scouts of America camp in Pennsylvania