Trion may refer to the following:
- Trion, Georgia – a town in Chattooga County, Georgia, United States
- Alpha Trion – the name of several fictional characters in the various Transformers universes
- Trion (neural networks) – a localized group of neurons in the cortex and a basic unit in the trion model
- Trion (physics) – a quasiparticle in a solid
- Trion Worlds - a video game developer and publisher