Deficiency
Naked mole rats lack cutaneous C fibers reactive to substance P (SP) and many small neurons that are normally SP-positive. Thus, these animals are insensitive to pain when painful stimuli are administered to the skin. New studies have shown that when the function of SP is genetically disrupted in mice, the animals demonstrated reduced responses to painful stimuli. Moreover, the response to capsaicin was absent or severely reduced in knockout mice.
Read more about this topic: Substance P
Famous quotes containing the word deficiency:
“Free verse leaves out the meter and makes up
For the deficiency by church intoning.
Free verse, so called, is really cherished prose....”
—Robert Frost (1874–1963)
“Shakespeare’s fault is not the greatest into which a poet may fall. It merely indicates a deficiency of taste.”
—Denis Diderot (1713–1784)
“It is easier to discover a deficiency in individuals, in states, and in Providence, than to see their real import and value.”
—Georg Wilhelm Friedrich Hegel (1770–1831)