Stine is a surname. Notable persons with that name include:
- Brad Stine (born 1960), American comedian and author
- Charles Stine (1882–1954), American chemist
- Clifford Stine (1906–1986), American cinematographer of horror films
- G. Harry Stine (1928–1997), American model rocketeer and author
- Jean Marie Stine (born 1945), American science fiction author and publisher
- Lee Stine (1913–2005), American professional baseball player
- R. L. Stine (born 1943), American novelist of youth literature
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