Technology
The DNA sequencing is done on a chip that contains many ZMWs. Inside each ZMW, a single active DNA polymerase with a single molecule of single stranded DNA template is immobilized to the bottom through which light can penetrate and create a visualization chamber that allows monitoring of the activity of the DNA polymerase at a single molecule level. The signal from a phospho-linked nucleotide incorporated by the DNA polymerase is detected as the DNA synthesis proceeds which results in the DNA sequencing in real time.
Read more about this topic: Single Molecule Real Time Sequencing
Famous quotes containing the word technology:
“Technology is not an image of the world but a way of operating on reality. The nihilism of technology lies not only in the fact that it is the most perfect expression of the will to power ... but also in the fact that it lacks meaning.”
—Octavio Paz (b. 1914)
“Radio put technology into storytelling and made it sick. TV killed it. Then you were locked into somebody else’s sighting of that story. You no longer had the benefit of making that picture for yourself, using your imagination. Storytelling brings back that humanness that we have lost with TV. You talk to children and they don’t hear you. They are television addicts. Mamas bring them home from the hospital and drag them up in front of the set and the great stare-out begins.”
—Jackie Torrence (b. 1944)
“Our technology forces us to live mythically, but we continue to think fragmentarily, and on single, separate planes.”
—Marshall McLuhan (1911–1980)