RCT may stand for:
- Random conical tilt, a technique used in Cryo-electron microscopy
- Randomized controlled trial, or randomized clinical trial
- Rational Choice Theory - a framework for understanding social and economic behavior
- Regents Competency Test, an alternative standardized test for special education high school students in New York State
- Regimental combat team
- Rehabilitation and Research Centre for Torture Victims
- Relational-cultural therapy
- Reverse cholesterol transport, pathway by which peripheral cell cholesterol can be returned to the liver for recycling to extrahepatic tissues, hepatic storage, or excretion into the intestine in bile.
- Reverse conducting thyristor
- Rhondda Cynon Taf, a county borough in Wales, UK
- Ring compression test, is an accurate technique to determine the true stress-true strain curve in typical metal-forming operations, and its accuracy was shown at high temperatures and low strain rates.
- Ritchey-Chrétien telescope
- RollerCoaster Tycoon (series), a video game series
- RollerCoaster Tycoon, the first game in the series
- Root canal therapy, dental treatment to treat nerve damage of the tooth
- Rose City Transit, a former mass transit company in Portland, Oregon
- Royal Corps of Transport
- Rugby Club Toulonnais, a rugby union club from Toulon, France
- Rural Community Transportation, a public bus system in Vermont