The initialism QCD may refer to:
- Quantum chromodynamics, the theory describing the Strong Interaction
- Quantum circuit diagram
- Quality, Cost, Delivery, a three-letter acronym used in lean manufacturing
- Quintessential Player, formerly known as Quintessential CD
- Quitclaim Deed, a deed of property from one party to another without warranties or defense of the deed
- Quad City DJ's, Southern rap group
- Quote-Comma-Delimited known also as Comma-separated values
- Quick Control Dial, a control on many DSLR cameras