Perutz is a surname. Notable people with the surname include:
- Hugo Perutz ∞ Adele Goldschmidt
- Max (Ferdinand) Perutz (1914, Vienna – 2002), Jewish Austrian-British molecular biologist
∞ Gisela Clara Peiser, sister of Lily Palmer- Robin Perutz (born 1949), son of Max, chemist
- Max (Ferdinand) Perutz (1914, Vienna – 2002), Jewish Austrian-British molecular biologist
- Adolf Perutz
- Otto Perutz (1847, Teplice – 1922), Jewish Czech-German engineer
- Benedikt Perutz ∞ Emilie Österreicher
- (Leopold) "Leo" Perutz (1882, Prague – 1957), Jewish Czech-Austrian novelist and mathematician
∞ Ida Weil, Grete Hamburger
- (Leopold) "Leo" Perutz (1882, Prague – 1957), Jewish Czech-Austrian novelist and mathematician
- Alfred Perutz (1885, Trieste – 1934), dermatologist and syphilidologist
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