Periodic Paralysis - Treatment

Treatment

Treatment of the periodic paralyses usually includes carbonic anhydrase inhibitors (such as acetazolamide or dichlorphenamide), taking supplemental oral potassium chloride and a potassium-sparing diuretic (for hypos) or avoiding potassium (for hypers), thiazide diuretics to increase the amount of potassium excreted by the kidneys (for Hypers), and significant lifestyle changes including tightly controlled levels of exercise or activity. However, the exact gene mutation, the ion channel affected, and the amount of genetic change or expression can have significant impact on disability and treatment.

Treatment of Andersen-Tawil syndrome is similar to that for other types of periodic paralysis. However, Pacemaker insertion or an implantable cardioverter-defibrillator may be required to control cardiac symptoms.

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