Pdk1

PDK1

Identifiers Symbol PDK1 External IDs OMIM: 602524 MGI: 1926119 HomoloGene: 20576 ChEMBL: 4766 GeneCards: PDK1 Gene EC number 2.7.11.2

Gene Ontology
Molecular function	• two-component sensor activity • protein kinase activity • pyruvate dehydrogenase (acetyl-transferring) kinase activity • ATP binding
Cellular component	• mitochondrion • mitochondrial matrix
Biological process	• glucose metabolic process • pyruvate metabolic process • small GTPase mediated signal transduction • regulation of acetyl-CoA biosynthetic process from pyruvate • peptidyl-histidine phosphorylation • small molecule metabolic process
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 5163 228026 Ensembl ENSG00000152256 ENSMUSG00000006494 UniProt Q15118 Q8BFP9 RefSeq (mRNA) NM_002610.3 NM_172665.4 RefSeq (protein) NP_002601.1 NP_766253.2 Location (UCSC) Chr 2:
173.42 – 173.49 Mb Chr 2:
71.87 – 71.9 Mb PubMed search

Pyruvate dehydrogenase lipoamide kinase isozyme 1, mitochondrial is an enzyme that in humans is encoded by the PDK1 gene. It codes for an isozyme of pyruvate dehydrogenase kinase (PDK).