Pancreatic Cancer

Pancreatic cancer is a malignant neoplasm originating from transformed cells arising in tissues forming the pancreas. The most common type of pancreatic cancer, accounting for 95% of these tumors, is adenocarcinoma (tumors exhibiting glandular architecture on light microscopy) arising within the exocrine component of the pancreas. A minority arise from islet cells, and are classified as neuroendocrine tumors. The signs and symptoms that eventually lead to the diagnosis depend on the location, the size, and the tissue type of the tumor, and may include abdominal pain, lower back pain, and jaundice (if the tumor compresses the bile duct).

Pancreatic cancer is the fourth most common cause of cancer-related deaths in the United States and the eighth worldwide. Pancreatic cancer has a poor prognosis: for all stages combined, the 1- and 5-year relative survival rates are 25% and 6%, respectively; for local disease the 5-year survival is approximately 20% while the median survival for locally advanced and for metastatic disease, which collectively represent over 80% of individuals, is about 10 and 6 months respectively.

Read more about Pancreatic CancerSigns and Symptoms, Risk Factors, Diagnosis, Pathophysiology, Prevention, Prognosis

Other articles related to "pancreatic cancer, pancreatic, cancer":

Surgical Outcomes Analysis And Research
... The group focuses on pancreatic cancer as well as other gastrointestinal and hepatobiliary malignancies ... Additionally, SOAR participates in groundbreaking pancreatic cancer biomarker discovery ... With rigorous proteomic assessment of blood, bile, and pancreatic fluid, they aspire to utilize biomarkers that will enable early diagnosis of pancreatic ...
Pancreatic Cancer - Prognosis
... Exocrine pancreatic cancer (adenocarcinoma and less common variants) typically has a poor prognosis, partly because the cancer usually causes no symptoms early on, leading to locally advanced or metastatic disease ... Pancreatic cancer may occasionally result in diabetes ... hampered, and it has been suggested the cancer can also prompt the onset of diabetes and vice versa ...
SULF1 - Role in Cancer - Pancreatic Cancer
... Sulf1 mRNA expression in pancreatic cancer differed from ovarian and liver cancer ... Only 50% of pancreatic cancer cell lines tested exhibited a significant decrease in Sulf1 ... Further, in situ hybridization demonstrated that Sulf1 mRNA expression was not uniformly absent in pancreatic cancer tissue ...
Pancreatic Ductal Carcinoma - Treatment - Exocrine Pancreas Cancer - Chemotherapy
... improvement in median survival duration in patients with advanced pancreatic cancer ... trial, reported in 2005, involved 569 patients with advanced pancreatic cancer, led the US FDA in 2005 to license erlotinib (Tarceva) in combination with gemcitabine as a palliative regimen for pancreatic cancer ...
Pancreatic Ductal Carcinoma - Prevention - Screening
... People who may have a high risk of pancreatic cancer due to a family history can be followed, but there is no consensus on what constitutes optimal monitoring ... People with pancreatic cancer themselves, or family members, may wish to participate in the activities at a research facility, or identify a pancreas ... called mesothelin in the urine or blood, which is a biomarker for pancreatic cancer ...

Famous quotes containing the word cancer:

    I wish more and more that health were studied half as much as disease is. Why, with all the endowment of research against cancer is no study made of those who are free from cancer? Why not inquire what foods they eat, what habits of body and mind they cultivate? And why never study animals in health and natural surroundings? why always sickened and in an environment of strangeness and artificiality?
    Sarah N. Cleghorn (1976–1959)