Pancreatic Cancer

Pancreatic cancer is a malignant neoplasm originating from transformed cells arising in tissues forming the pancreas. The most common type of pancreatic cancer, accounting for 95% of these tumors, is adenocarcinoma (tumors exhibiting glandular architecture on light microscopy) arising within the exocrine component of the pancreas. A minority arise from islet cells, and are classified as neuroendocrine tumors. The signs and symptoms that eventually lead to the diagnosis depend on the location, the size, and the tissue type of the tumor, and may include abdominal pain, lower back pain, and jaundice (if the tumor compresses the bile duct).

Pancreatic cancer is the fourth most common cause of cancer-related deaths in the United States and the eighth worldwide. Pancreatic cancer has a poor prognosis: for all stages combined, the 1- and 5-year relative survival rates are 25% and 6%, respectively; for local disease the 5-year survival is approximately 20% while the median survival for locally advanced and for metastatic disease, which collectively represent over 80% of individuals, is about 10 and 6 months respectively.

Read more about Pancreatic CancerSigns and Symptoms, Risk Factors, Diagnosis, Pathophysiology, Prevention, Prognosis

Other articles related to "pancreatic cancer, cancer, pancreatic":

Pancreatic Ductal Carcinoma - Prevention - Screening
... People who may have a high risk of pancreatic cancer due to a family history can be followed, but there is no consensus on what constitutes optimal monitoring ... People with pancreatic cancer themselves, or family members, may wish to participate in the activities at a research facility, or identify a pancreas tumor registry ... called mesothelin in the urine or blood, which is a biomarker for pancreatic cancer ...
Pancreatic Ductal Carcinoma - Treatment - Exocrine Pancreas Cancer - Chemotherapy
... survival duration in patients with advanced pancreatic cancer ... Phase III randomised controlled trial, reported in 2005, involved 569 patients with advanced pancreatic cancer, led the US FDA in 2005 to license erlotinib (Tarceva) in ...
SULF1 - Role in Cancer - Pancreatic Cancer
... Sulf1 mRNA expression in pancreatic cancer differed from ovarian and liver cancer ... Only 50% of pancreatic cancer cell lines tested exhibited a significant decrease in Sulf1 ... hybridization demonstrated that Sulf1 mRNA expression was not uniformly absent in pancreatic cancer tissue ...
Surgical Outcomes Analysis And Research
... The group focuses on pancreatic cancer as well as other gastrointestinal and hepatobiliary malignancies ... SOAR participates in groundbreaking pancreatic cancer biomarker discovery ... rigorous proteomic assessment of blood, bile, and pancreatic fluid, they aspire to utilize biomarkers that will enable early diagnosis of pancreatic cancer and ...
Pancreatic Cancer - Prognosis
... Exocrine pancreatic cancer (adenocarcinoma and less common variants) typically has a poor prognosis, partly because the cancer usually causes no symptoms early on, leading to locally advanced or metastatic disease at ... Pancreatic cancer may occasionally result in diabetes ... Insulin production is hampered, and it has been suggested the cancer can also prompt the onset of diabetes and vice versa ...

Famous quotes containing the word cancer:

    We “need” cancer because, by the very fact of its incurability, it makes all other diseases, however virulent, not cancer.
    Gilbert Adair, British author, critic. “Under the Sign of Cancer,” Myths and Memories (1986)