History
Nitrous oxide as a single gas was first used as a medical analgesic in 1844 by American dentist Horace Wells, growing in popularity in the late 1800s. Negative side effects were found from the hypoxia caused by a lack of oxygen, and the requirement to have at least 21% oxygen content in the gas was discovered (the same percentage as in air).
In 1911, the anaesthetist Arthur Ernest Guedel first described the use of self-administration of a nitrous oxide and oxygen mix.
It was not until 1961 that the first paper was published by Michael Tunstall et al. describing the administration of a pre-mixed 50:50 nitrous oxide and oxygen mix, which led to the commercialisation of the product.
Read more about this topic: Nitrous Oxide And Oxygen
Famous quotes containing the word history:
“The only thing worse than a liar is a liar that’s also a hypocrite!
There are only two great currents in the history of mankind: the baseness which makes conservatives and the envy which makes revolutionaries.”
—Edmond De Goncourt (1822–1896)
“The basic idea which runs right through modern history and modern liberalism is that the public has got to be marginalized. The general public are viewed as no more than ignorant and meddlesome outsiders, a bewildered herd.”
—Noam Chomsky (b. 1928)
“History is not what you thought. It is what you can remember. All other history defeats itself.
In Beverly Hills ... they don’t throw their garbage away. They make it into television shows.
Idealism is the despot of thought, just as politics is the despot of will.”
—Mikhail Bakunin (1814–1876)