Mir-34 Micro RNA Precursor Family
The mir-34 microRNA precursor family are non-coding RNA molecules that, in mammals, give rise to three major mature miRNAs. The miR-34 family members were discovered computationally and later verified experimentally. The precursor miRNA stem-loop is processed in the cytoplasm of the cell, with the predominant miR-34 mature sequence excised from the 5' arm of the hairpin. The mature miR-34a is a part of the p53 tumor suppressor network of proteins; therefore, it is hypothesized that miR-34 dysregulation is involved in the development of some cancers.
Read more about Mir-34 Micro RNA Precursor Family: The MiR-34 Family, Targets of MiR-34, Mir-34 Inhibits Human P53-mutant Gastric Cancer Tumorspheres
Famous quotes containing the word family:
“Children’s lives are not shaped solely by their families or immediate surroundings at large. That is why we must avoid the false dichotomy that says only government or only family is responsible. . . . Personal values and national policies must both play a role.”
—Hillary Rodham Clinton (20th century)