Mir-34 Micro RNA Precursor Family
The mir-34 microRNA precursor family are non-coding RNA molecules that, in mammals, give rise to three major mature miRNAs. The miR-34 family members were discovered computationally and later verified experimentally. The precursor miRNA stem-loop is processed in the cytoplasm of the cell, with the predominant miR-34 mature sequence excised from the 5' arm of the hairpin. The mature miR-34a is a part of the p53 tumor suppressor network of proteins; therefore, it is hypothesized that miR-34 dysregulation is involved in the development of some cancers.
Read more about Mir-34 Micro RNA Precursor Family: The MiR-34 Family, Targets of MiR-34, Mir-34 Inhibits Human P53-mutant Gastric Cancer Tumorspheres
Famous quotes containing the word family:
“There are one or two rules,
Half-a-dozen, maybe,
That all family fools,
Of whatever degree,
Must observe if they love their profession.”
—Sir William Schwenck Gilbert (1836–1911)