The MiR-34 Family
In mammals, three miR-34 precursors are produced from two transcriptional units. The human miR-34a precursor is transcribed from chromosome 1. The miR-34b and miR-34c precursors are co-transcribed from a region on chromosome 11, apparently as part of a transcript known as BC021736.
Expression of miR-34a in mouse is observed in all tissues examined but is highest in brain. miR-34b and -c are relatively less abundant in most tissues, but are the predominant miR-34 species in lung. The presence of miR-34 products has also been confirmed in embryonic stem cells.
Read more about this topic: Mir-34 Micro RNA Precursor Family
Famous quotes containing the word family:
“Freud is all nonsense; the secret of neurosis is to be found in the family battle of wills to see who can refuse longest to help with the dishes. The sink is the great symbol of the bloodiness of family life.”
—Julian Mitchell (20th century)