Medical Uses
Metformin is primarily used for type 2 diabetes, but is increasingly being used in polycystic ovary syndrome (PCOS), non-alcoholic fatty liver disease (NAFLD) and premature puberty, three other diseases that feature insulin resistance; these indications are still considered experimental. The benefit of metformin in NAFLD has not been extensively studied and may be only temporary; although some randomized controlled trials have found significant improvement with its use, the evidence is still insufficient.
Read more about this topic: Metformin
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—Louise Lague (20th century)
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—Catherine E. Beecher (1800–1878)