Career At Washington University
By 1910, Dr. Loeb had acquired a national reputation for his work on cancer. He was invited to become the director of the Barnard Free Skin & Cancer Hospital in St. Louis, a center that was attached to Washington University. This was a novel institution, in that its emphasis was on clinical research, even though Barnard was indeed a hospital for humans. Over the succeeding several years, Loeb showed clearly that the growth of certain epithelial malignancies in animals could be modulated by removal of the ovaries. That work predated clinical application of the same concept in human breast cancer by several decades.
In 1915, Dr. Loeb was appointed as professor of comparative pathology at Washington University School of Medicine (WUSM). Having long deferred a family life to concentrate on his research, he finally married Dr. Georgiana Sands (another physician) in 1922, at the age of 53. She became not only his spouse, but also his scientific, administrative, and literary partner for the remainder of their lives together. In 1924, Dr. Loeb was given the chairmanship of pathology at WUSM; thereafter, he continued his work on tissue transplantation and cell culture, as well as research on endocrine disease. Loeb was known as a patient, kind, and helpful mentor to younger colleagues in the department.
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