Kleine-Levin Syndrome - First Onset

First Onset

About 90% of KLS patients associate an event with their first KLS episode. This event is most often a type of infection or cold, but may also be associated with stress, sleep deprivation, alcohol, physical exertion, head trauma or even traveling and marijuana use. This causes some to think that there may be some immunological link, but so far there is no clear proof of this. Only a quarter of KLS patients report events triggering subsequent episodes.

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